Of course, I have more than one reason I don't use drugs. For instance, most mood-altering drugs tend to degrade other pleasures and interests, which I find more important, like clear thinking. Clear thinking is a miracle, really. To be able to see the world in our minds, and fashion it as we will, and communicate these thoughts to others, clearly (as I'm trying to do now) is a blessing from the Cosmos or from God, or however you wish to characterize it. But drugs all too often inhibit this.
Another reason I don't use drugs: I don't want to support drug cartels. The suffering we Americans hand-down to these poor nations is reprehensible. I shall not be part of it. This video is yet another example of this specific horror visiting our brothers and sisters, our neighbors, in Mexico:
And here's yet another horrible story just today (by Anderson Cooper, CNN):